J. A. H. Murray University of Cambridge
Dr Andrew J Murray
University Senior Lecturer in Mammalian Physiology
Office Phone: 01223 333863
J. A. H. Murray University of Cambridge, Research Interests
Mitochondrial function in health and disease
My research is concerned with mitochondrial function:
- how this is altered in metabolic diseases, during development and ageing, and with changes in diet, exercise and oxygen
- what effects these changes have on physiological performance.
We aim to elucidate the causes of mitochondrial dysfunction and the impact this has on function at the level of the tissue, intact organ and whole body.
cardiovascular physiology ; hypoxia ; cardiometabolic disease ; oxidative stress
Most recent publications are listed on PubMed.
Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism. Ashmore T, Roberts LD, Morash AJ, Kotwica AO, Finnerty J, West JA, Murfitt SA, Fernandez BO, Branco C, Cowburn AS, Clarke K, Johnson RS, Feelisch M, Griffin JL, Murray AJ. BMC Biol. 2015 Dec 22;13:110.
Inorganic nitrate promotes the browning of white adipose tissue through the nitrate-nitrite-nitric oxide pathway. Roberts LD, Ashmore T, Kotwica AO, Murfitt SA, Fernandez BO, Feelisch M, Murray AJ, Griffin JL. Diabetes. 2015 Feb;64(2):471-84.